giovedì 28 giugno 2007

DEMENZA E COGNIZIONE AIUTATE DALL’ACIDO FOLICO

Lo studio FACIT Folic Acid and Carotid Intima-media Thickness ha dimostrato che la somministrazione di acido folico in pazienti di età avanzata permette un miglioramento delle loro capacità cognitive e previene dal rischio della demenza senile.

Con l’aumento dell’età le capacità cognitive diminuiscono, soprattutto per quanto riguarda la velocità di processamento delle informazioni, e tale diminuizione è stata studiata in termini biologici. Si è visto che tali mutamenti si associano con basse concentrazioni di folati e l’aumento delle concentrazioni di omocisteina plasmatici.
Tali indicatori possono pertanto essere considerati fattori di rischio nell’insorgenza della demenza in età anziana.

Lo studio FACIT ha coinvolto 818 soggetti, divisi casualmente in due gruppi. Il gruppo sperimentale riceveva 800milligrammi al giorno di Acido Folico, mentre al gruppo di controllo veniva somministrato soltanto un placebo. La durata dello studio era di tre anni.

I risultati hanno mostrato che le funzioni cognitive dei soggetti a quali era stato somministrato Acido Folico erano significativamente migliori di quelle del gruppo di controllo. Nello specifico i valori migliori si sono registrati nella memoria e nella velocità di processamento delle informazioni.

Foto by valentina_virtual

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